Non-animal Alternatives and Reduction in Laboratory Animal Use

Alternatives in animal testing.

1Division of Hematology/Oncology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 2Division of Cardiology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 3Department of Pathology, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610...

Alternatives to Animal Experimentation

This special issue of ALTEX is publicising what the 3R Research Foundation has achieved in the past and what projects are currently underway. This special issue is intended to improve awareness of the projects funded by the Foundation and to provide a training tool. The first section includes updated descriptions of 20 projects from the past ten years. These projects, involving basic research, ...

Alternatives to Animal Experimentation

Animal allergen sensitization in veterinarians and laboratory animal workers.

BACKGROUND Animals secrete allergens into the environment and exposure to these in the workplace may cause sensitization. AIMS To identify the frequency of animal allergen sensitization and symptoms in animal workers. METHODS Using skin prick tests (SPT), we assessed sensitization to 15 mammal and bird allergens in animal workers and controls. We also recorded symptoms and pulmonary functio...

Alternatives to Animal Use for the LAL-Assay

testing for the absence of pyrogenic (fever inducing) substances (Ding and Ho, 2001) is of utmost importance for a safe administration of parenteral medicines (or “medicines for parenteral use”) such as infusion solutions, plasma derivatives, vaccines, cell therapeutics, gene therapeutics, and tissues. In general, the group of pyrogenic agents able to activate monocytes includes bacteria, virus...